Fig. 7From: Targeted quantitation of CFTR protein expression in vivo using immunoprecipitation & parallel reaction monitoring tandem mass spectrometryhCFTR level measured by the developed method in mouse lung treated with three different LNPs formulations. 50 mg of mouse lung tissue was analyzed. Five animals were dosed for testing each formulation. Streptavidin magnetic beads and biotinylated anti-CFTR antibody were used for IP. Absolute quantification of hCFTR protein was based on the calibration curve of CFTR peptide LSLVPDSEQGEAILPRBack to article page