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Fig. 2 | Translational Medicine Communications

Fig. 2

From: Circulating neutrophil extracellular trap (NET)-forming ‘rogue’ neutrophil subset, immunotype [DEspR + CD11b +], mediate multi-organ failure in COVID-19—an observational study

Fig. 2

Comparative quantitative analysis of circulating NET + Ns using automated shape analysis in COVID-19 peripheral blood smears. A Diagram of circularity index determination and B corresponding frequency graph of the spread of circularity indices calculated by automated shape-analysis algorithm with designation of < 0.8 as cut-off for assignment of NET-forming neutrophils or [NET + Ns]. C Frequency curve of number of COVID-19 subjects (n = 36) with DEspR + CD11b + [NET + Ns]: median 53.4% (IQR: 28.2 – 68.5%), mean ± sd: 51.5% ± 24.8%. D Frequency curve of number of COVID-19 subjects (n = 36) with DEspR(-)CD11b( ±) [NET + Ns]: median 1.0% (IQR: 0.2 – 3.1%); mean ± sd: 1.8% ± 1.9%

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Translational Medicine Communications

ISSN: 2396-832X

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