Fig. 3

Treg identity and maturation status phenotyping. a Percentage of cells expressing the combination of specified markers in batches of TX200-TR101 manufactured from patients with ESRD (n = 4) and healthy donors (n = 10). b Percentage of naïve (CD4⁺/CD45RA⁺/CD27⁺), effector memory 1 (CD4⁺/CD45RA⁻/CD27⁺), effector memory 2 (CD4⁺/CD45RA⁻/CD27⁻) and effector (CD4⁺/CD45RA⁺/CD27⁻) cells in batches of TX200-TR101 manufactured from patients with ESRD (n = 4) and healthy donors (n = 10). c The inset panel shows the same data as panel b for effector memory 1, effector memory 2 and effector cells plotted on a larger y-axis scale. For each boxplot, the box represents the interquartile range; the median value divides the box in two parts; whiskers represent minimum and maximum values; X represents the mean value. Individual data points (other than minimum and maximum values) are shown as open circles. No statistically significant differences in the means between the two populations (ESRD patients vs healthy donors) were observed