Fig. 7

Comparison of preclinical vs. clinical PFS fixed effects of ICB therapies. The preclinical (MSR) and clinical (PFS HR) estimates from the meta-analyses for each treatment were plotted against each other (dots) along with their 95% confidence intervals. The red dotted line represents the slope of the regression passing through the origin of the clinical efficacy estimates on the preclinical ones and its 95% confidence interval. The black dotted line represents the perfect correspondence between preclinical and clinical estimates of efficacy. This figure corresponds to the data presented in Table 5