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Table 6 Prediction MSE from the clinical and preclinical models. The leave-one-out cross-validation error is shown for the clinical model. For the preclinical models, the errors derived from the cancer-type specific predictions of the corresponding measures of clinical efficacy are shown for each of the preclinical variables considered (MSR and HR)

From: Meta-analysis of preclinical measures of efficacy in immune checkpoint blockade therapies and comparison to clinical efficacy estimates

Model

OS HR MSE

PFS HR MSE

Clinical CV

0.0184

0.0836

Preclinical MSR

0.0221

0.0901

Preclinical HR

0.1181

0.2595