Fig. 3
A Mice with 786-O tumors were administered 0.56 mg iMN041 SC in FS-14 qod or PBS (n = 10 per group). Graph of 786-O growth in iMN041 treated versus vehicle control animals. Mean tumor volume +/- SD at study initiation was 111 mm3 +/- 16.7. B, C Mice with Caki-1 tumors were administered 0.56 mg iMN041 SC in FS-14 qod or PBS (n = 10 per group). Mean tumor volume +/- SD at study initiation was 98 mm3 +/- 18.4. B Graph of Caki-1 growth in iMN041 treated versus control animals. C Survival proportion in Caki-1 implants, treated versus control animals. (> 42 days (undefined) vs. 42 days, p = 0.061). D Mice with Caki-1 tumors were administered 0.8 mg iMN041 SC in FS-19 qod or PBS (n = 10 per group). Graph of Caki-1 growth in iMN041 treated versus control animals. Mean tumor volume +/- SD at study initiation was 66 mm3 +/- 11.5