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Fig. 1 | Translational Medicine Communications

Fig. 1

From: Co-expression analysis of transcriptomic data from cancer and healthy specimens reveals rewiring of proteasome genes and an interaction with the XPO1 gene across several tumour types

Fig. 1

A Matrices representing R Pearson correlation coefficients for gene co-expression within a set of 78 genes (38 proteasome genes, 38 genes encoding Exportin-1 interacting proteins and 2 control genes) for 605 specimens of healthy lung from the GTEx and 601 specimens of Lung adenocarcinoma from the TCGA. The cell's colour intensity is proportional to the R Pearson correlation between the gene pairs. Range of R values for Healthy Lung: 0.000083-0.967020; range for Lung Adenocarcinoma: 0.000152-0.962849. The gradient scale colour is available at https://figshare.com/projects/ProteasomeGeneExpression/171357. B Matrices representing R Pearson correlation coefficients for gene co-expression within a set of 78 genes (38 proteasome genes, 38 genes encoding Exportin-1 interacting proteins and 2 control genes) for 360 specimens of healthy pancreas from the GTEx and 183 specimens of Pancreas adenocarcinoma from the TCGA. The cell's colour intensity is proportional to the R Pearson correlation between the gene pairs. Range of R values for Healthy Pancreas: 0.003631-0.968954; range for Pancreas Adenocarcinoma: 0.000224-0.978171. The gradient scale colour is available at https://figshare.com/projects/ProteasomeGeneExpression/171357

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