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  1. Cumulative research show association of neutrophils and neutrophil extracellular traps (NETs) with poor outcomes in severe COVID-19. However, to date, there is no curative intent therapy able to block neutroph...

    Authors: Victoria L. M. Herrera, Nicholas A. Bosch, Judith J. Lok, Mai Q. Nguyen, Kaitriona A. Lenae, Joanne T. deKay, Sergey V. Ryzhov, David B. Seder, Nelson Ruiz-Opazo and Allan J. Walkey
    Citation: Translational Medicine Communications 2023 8:12
    Content type: Research Published on:

  2. Gene therapy manipulates or modifies a gene that provides a new cellular function to treat or correct a pathological condition, such as cancer. The approach of using gene manipulation to modify patient’s cells...

    Authors: Shivani Thoidingjam, Sushmitha Sriramulu, Svend Freytag, Stephen L. Brown, Jae Ho Kim, Indrin J. Chetty, Farzan Siddiqui, Benjamin Movsas and Shyam Nyati
    Citation: Translational Medicine Communications 2023 8:11
    Content type: Review Published on:

  3. Rheumatoid Arthritis is one of the most common autoimmune diseases, causing irreversible joint damage and disability. Methotrexate (MTX) is the gold standard drug for this. The low cost, easy availability and ...

    Authors: Harjit Singh Nalwa, Peeyush Prasad, Nirmal Kumar Ganguly, Ved Chaturvedi and Shivani Arora Mittal
    Citation: Translational Medicine Communications 2023 8:10
    Content type: Review Published on:

  4. Preclinical studies have demonstrated the potential use of induced pluripotent stem cells (iPSCs) to treat cardiovascular disease (CVD). In vivo preclinical studies conducted on animal models (murine, porcine,...

    Authors: Ryan Bellman, Jishizhan Chen, Lidan Chen, Nikolitsa Nomikou, Janice Tsui, George Hamilton and Wenhui Song
    Citation: Translational Medicine Communications 2023 8:9
    Content type: Research Published on:

  5. Host response to the human immune deficiency virus (HIV) involves both the innate and adaptive immune systems. As part of the innate immune system, the killer cell immunoglobulin-like receptors (KIRs) found o...

    Authors: John Mukisa, Marion Amujal, Obondo J. Sande, Moses L. Joloba, Daudi Jjingo, David P. Kateete, Graeme Mardon, Mogomotsi Matshaba, Neil Hanchard and Jill A. Hollenbach
    Citation: Translational Medicine Communications 2023 8:8
    Content type: Review Published on:

  6. Electronic health records (EHRs) and linked biobanks have tremendous potential to advance biomedical research and ultimately improve the health of future generations. Repurposing EHR data for research is not w...

    Authors: Cosby G. Arnold, Brandon Sonn, Frederick J. Meyers, Alexis Vest, Richie Puls, Estelle Zirkler, Michelle Edelmann, Ian M. Brooks and Andrew A. Monte
    Citation: Translational Medicine Communications 2023 8:7
    Content type: Review Published on:

  7. Prophylactic platelet transfusion is given to patients when the platelet count is less than ten thousand to prevent clinically significant bleeding till platelet engraftment is documented. Despite a very low p...

    Authors: Zainab Ghias, Uzma Zaidi, Munira Borhany, Shafaq Abdul Samad, Noureen Durrani, Mushkbar Fatima, Sidra Zafar, Aisha Jamal and Tahir Shamsi
    Citation: Translational Medicine Communications 2023 8:6
    Content type: Research Published on:

  8. This window of opportunity trial evaluated the safety of intratumoral Copaxone® and profiled immune markers in biopsies before and after treatment.

    Authors: Joaquina C. Baranda, Ghulam Rehman Mohyuddin, Andrés M. Bur, Yelizaveta Shnayder, Kyle R. Sweeney, Kiran Kakarala, Megan Prouty, Harsh Pathak, Rajni Puri, Amrita Mitra, Rashna Madan, M. Laird Forrest, Aric Huang, Scott Weir, Andrew K. Godwin, Nabil A. Alhakamy…
    Citation: Translational Medicine Communications 2023 8:5
    Content type: Research Published on:

  9. Intrathecal (IT) catheter delivery of baclofen via continuous infusion using an implantable pump is an important means of treating patients with severe spasticity. We evaluated the impact of IT catheter tip pl...

    Authors: Brian A. Duclos, Cindy Roegge, Howard Dobson, Scott Haller, Jeff Bodner, Sanjana Pannem, Janelle Gesaman and Amin Nourmohammadi
    Citation: Translational Medicine Communications 2023 8:4
    Content type: Research Published on:

  10. The BRAF and MEK inhibitors combined strategies have dramatically changed the outcome of BRAF-mutated metastatic melanoma patients. However, despite the initial promising results, the onset of primary or acqui...

    Authors: Valentina Belli, Stefania Napolitano, Vincenzo De Falco, Gabriella Suarato, Alessandra Perrone, Luigi Pio Guerrera, Giulia Martini, Carminia Maria Della Corte, Erika Martinelli, Floriana Morgillo, Mimmo Turano, Maria Furia, Giuseppe Argenziano, Davide Ciardiello, Fortunato Ciardiello and Teresa Troiani
    Citation: Translational Medicine Communications 2023 8:3
    Content type: Research Published on:

  11. Hypoxic zones exist in solid tumors, where oxygen levels are significantly lower than in normal tissues. Hypoxia makes chemo-radiation therapeutics less effective and renders the metastatic potential more favo...

    Authors: Muzamil Farooq, Gh. Rasool Bhat, Syed Besina, Natasha Thakur, Sheikh Zahoor, Rafiq A. Rather, Ifra Mushtaq, Sadaf Dar, Bilal Rah, Ajaz A. Bhat, Muzafar A. Macha and Dil Afroze
    Citation: Translational Medicine Communications 2023 8:2
    Content type: Research Published on:

  12. RLS-0071 is a novel 15 amino acid peptide dual-targeting anti-inflammatory inhibitor of complement and neutrophil effectors. RLS-0071 inhibits classical complement pathway activation at C1 and blocks the enzym...

    Authors: Jessica Goss, Pamela Hair, Parvathi Kumar, Giuseppina Iacono, Laura Redden, Gaetano Morelli, Neel Krishna, Ulrich Thienel and Kenji Cunnion
    Citation: Translational Medicine Communications 2023 8:1
    Content type: Research Published on:

  14. Acute inflammation is the body’s immediate and well-coordinated response to injury, which if not resolved can lead to a state of chronic inflammation and is an important component of aging-associated pathologi...

    Authors: Asha Jaja-Chimedza, Steven Hirsh, Dainian Bruce, Tony Bou-Sliman, Steven Joyal and Andrew G. Swick
    Citation: Translational Medicine Communications 2022 7:25
    Content type: Research Published on:

  15. Clinical translation from bench to bedside often remains challenging even despite promising preclinical evidence. Among many drivers like biological complexity or poorly understood disease pathology, preclinic...

    Authors: Natascha Ingrid Drude, Lorena Martinez-Gamboa, Meggie Danziger, Anja Collazo, Silke Kniffert, Janine Wiebach, Gustav Nilsonne, Frank Konietschke, Sophie K. Piper, Samuel Pawel, Charlotte Micheloud, Leonhard Held, Florian Frommlet, Daniel Segelcke, Esther M. Pogatzki-Zahn, Bernhard Voelkl…
    Citation: Translational Medicine Communications 2022 7:24
    Content type: Review Published on:

  16. Diabetic dyslipidemia is a complex multidimensional abnormality. However, earlier studies did not focus on the prevalence of various patterns of dyslipidemia. We categorized dyslipidemia into three groups. Sin...

    Authors: Amirhossein Yadegar, Fatemeh Mohammadi, Soghra Rabizadeh, Reihane Qahremani, Alireza Esteghamati and Manouchehr Nakhjavani
    Citation: Translational Medicine Communications 2022 7:23
    Content type: Research Published on:

  17. The pathogenesis of the novel described multisystem inflammatory syndrome in children (MIS-C) and Kawasaki disease (KD) is still debated as it is not clear if they are the same or different nosological entitie...

    Authors: Alice Castaldo, Carolina D’Anna, Monica Gelzo, Antonietta Giannattasio, Marco Maglione, Stefania Muzzica, Maddalena Raia, Giulia Scalia, Lorella Tripodi, Giuseppe Castaldo, Vincenzo Tipo, Domenico Grieco and Michela Grieco
    Citation: Translational Medicine Communications 2022 7:22
    Content type: Research Published on:

  18. Many variables have been studied in cancer patients. Nevertheless, an study that analyzes simultaneously physical, functional and biological variables in they from clinical, physical and statistical points of ...

    Authors: Justa Carmen Columbié Regüeiferos, Taira Teresa Batista Luna, Soraida Cándida Acosta Brooks, Maylet Planas Rodriguez, Larisa Zamora Matamoros, Beatríz Legrá Rodríguez, Arnolis Poll Fernández, José Luis García Bello, Arquímedes Montoya Pedrón, Maraelys Morales González, Julio Cesar Núñez Garcia, Esmirna Cascaret Fonseca and Luis Enrique Bergues Cabrales
    Citation: Translational Medicine Communications 2022 7:21
    Content type: Research Published on:

  20. Bloodstream infections (BSIs) are among the most lethal complications of liver transplantation (LT). Natural killer (NK) cells are an important component of innate immunity and play an essential role in infect...

    Authors: Masahiro Ohira, Yuki Imaoka, Koki Sato, Koki Imaoka, Ryosuke Nakano, Naoki Tanimine, Hiroyuki Tahara, Kentaro Ide, Tsuyoshi Kobayashi, Yuka Tanaka and Hideki Ohdan
    Citation: Translational Medicine Communications 2022 7:19
    Content type: Protocol Published on:

  21. Obesity increases the chance of developing insulin resistance. Numerous inflammatory markers have been linked to an increased risk of insulin resistance in obese individuals. Therefore, we performed a bibliome...

    Authors: Sa’ed H. Zyoud, Muna Shakhshir, Amani S. Abushanab, Amer Koni, Moyad Shahwan, Ammar A. Jairoun and Samah W. Al-Jabi
    Citation: Translational Medicine Communications 2022 7:18
    Content type: Research Published on:

  23. In the present study, the effect(s) of the immunomodulatory drug GLS-1027 on various cell types involved in inflammation were investigated. GLS-1027 reduced LPS-stimulated secretion of pro-inflammatory cytokin...

    Authors: Sagar B Kudchodkar, Paolo Fagone, Omkar U Kawalekar, Moonsup Jeong, Christine C Roberts, Hyojin Lee, Youngran Cho, Areum Gil, Yeeun Oh, Bohyun Jeon, Gee Ho Park, Young K Park, Ferdinando Nicoletti, Joel N Maslow and Kar Muthumani
    Citation: Translational Medicine Communications 2022 7:16
    Content type: Research Published on:

  25. Non-healing surgical wounds is a risk in certain patients. Recently, allogenic plasma-rich-platelet (PRP) is used such as regenerative treatment of different non-healing surgical wounds.

    Authors: Jesús Seco-Calvo, Julia Vidán-Estévez and Sergio Sánchez-Herráez
    Citation: Translational Medicine Communications 2022 7:14
    Content type: Research Published on:

  26. Translational research aims at reducing gaps between fundamental scientific discoveries and real-world applications. However, the trajectory of most scientific discoveries along the translation research contin...

    Authors: Gardy Lavertu, Ella Diendere, France Légaré, Hervé Tchala Vignon Zomahoun, Alfred Kodjo Toi, Mathilde Leblond, Nathalie Rheault, Étienne Audet-Walsh, Marie-Claude Beaulieu, Ali Ben Charif, Virginie Blanchette, Jean-Pierre Després, André Gaudreau, Caroline Rhéaume, Marie-Claude Tremblay and Jean-Sébastien Paquette
    Citation: Translational Medicine Communications 2022 7:13
    Content type: Commentary Published on:

  27. Elevated serum levels of serum amyloid A (SAA) are associated with increased risk of cardiovascular disease. In this study, we examine associations between allelic variation in the rs11024595 single nucleotide...

    Authors: Sofie Ahlin, Maja Löfgren, Magdalena Taube, Johanna C. Andersson-Assarsson, Markku Peltonen, Per-Arne Svensson, Peter Jacobson, Lena MS Carlsson and Kajsa Sjöholm
    Citation: Translational Medicine Communications 2022 7:12
    Content type: Research Published on:

  28. Collaboration between biomedical research and community-based primary health care actors is essential to translate evidence into clinical practice. However, little is known about the characteristics and impact...

    Authors: Jean-Sébastien Paquette, Hervé Tchala Vignon Zomahoun, Ella Diendere, Gardy Lavertu, Nathalie Rheault, Alfred Kodjo Toi, Mathilde Leblond, Étienne Audet-Walsh, Marie-Claude Beaulieu, Ali Ben Charif, Virginie Blanchette, Jean-Pierre Després, André Gaudreau, Caroline Rhéaume, Marie-Claude Tremblay and France Légaré
    Citation: Translational Medicine Communications 2022 7:11
    Content type: Review Published on:

  29. Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis and represents an important global public health issue. Single-nucleotide polymorphisms and INDELs are common genetic ...

    Authors: Débora C. R. F. Porchera, Diana F. V. B. Leal, Ana C. O. Braga, Pablo D. C. Pinto, Mayara N. Santana da Silva, Lucas C. Bezerra Santos, Cintia H. Braga da Silva, Giovana E. da Costa, Maria Clara da C. Barros, Aidalucy do S. C. de Athayde, Amanda de N Cohen-Paes, Cleonardo A. da Silva, Paulo P. de Assumpção, Ândrea K. C. Ribeiro-dos-Santos, Sidney E. B. dos Santos, Marianne R. Fernandes…
    Citation: Translational Medicine Communications 2022 7:10
    Content type: Research Published on:

  30. The cystic fibrosis transmembrane conductance regulator (CFTR) protein is a low-abundance membrane protein. The dysfunction of CFTR protein is the fundamental cause of cystic fibrosis (CF), a fatal genetic dis...

    Authors: Hui Wang, Yunxiang Dai, Nicholas Clark, Lianne Boeglin, Caroline Woo, Richard Wooster, Gang Sun and James C. Sullivan
    Citation: Translational Medicine Communications 2022 7:9
    Content type: Research Published on:

  31. Diffuse intrinsic pontine glioma (DIPG) is a notoriously difficult tumor to treat, with an overall survival of DIPG patients being only 11 months. One of the major obstacles for the effective treatment of DIPG...

    Authors: Rianne Haumann, John I. Bianco, Piotr M. Waranecki, Pieter J. Gaillard, Gert Storm, Mario Ries, Dannis G. van Vuurden, Gertjan J. L. Kaspers and Esther Hulleman
    Citation: Translational Medicine Communications 2022 7:8
    Content type: Research Published on:

  32. Cancer is considered one of the primary illnesses that cause morbidity and mortality in millions of people worldwide and due to its prevalence, there is undoubtedly an unmet need to discover novel anticancer d...

    Authors: Richa, Neha Sharma and Geetanjali Sageena
    Citation: Translational Medicine Communications 2022 7:7
    Content type: Review Published on:

  36. Dysregulation of antiviral immunity has been implicated in the progression of acute respiratory syndrome coronavirus 2 infection into severe cases of coronavirus disease of 2019 (COVID-19). Imbalances in the i...

    Authors: Gregory Thomas, Kristen Hirter, Elizabeth Frederick, Melissa Hausburg, Raphael Bar-Or, Yetti Mulugeta, Michael Roshon, Charles Mains and David Bar-Or
    Citation: Translational Medicine Communications 2022 7:3
    Content type: Research Published on:

  37. SARS-CoV-2 developed global-pandemic with millions of infections/deaths. As it is urgently necessary it is assumed that some blockers/inhibitors of ACE2 could be helpful to resist the binding of viral-spike Re...

    Authors: Amrita Banerjee, Mehak Kanwar, Dipannita Santra and Smarajit Maiti
    Citation: Translational Medicine Communications 2022 7:2
    Content type: Research Published on:

  38. Preeclampsia (PE) is a life-threatening disease characterized by elevated blood pressure and proteinuria. Predictive biomarkers of PE are needed, especially those predicting PE in early pregnancy. The aim of t...

    Authors: Sakari Joenväärä, Matilda Holm, Mayank Saraswat, Rahul Agarwal, Tiialotta Tohmola, Eero Kajantie, Katri Räikkönen, Hannele Laivuori, Pia M. Villa, Esa Hämäläinen and Risto Renkonen
    Citation: Translational Medicine Communications 2022 7:1
    Content type: Research Published on:

  39. Vaccination is an essential strategy for mitigating the COVID-19 pandemic. Besides its significance as a public health measure, vaccination is a sophisticated example of modern biotechnology. Since vaccination...

    Authors: Niklas Alexander Döbler and Claus-Christian Carbon
    Citation: Translational Medicine Communications 2021 6:27
    Content type: Review Published on:

  40. The COVID-19 pandemic remains an emerging public health crisis with serious adverse effects. The disease is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV--2) infection, targeting angioten...

    Authors: Hamid Reza Kouhpayeh, Farhad Tabasi, Mohammad Dehvari, Mohammad Naderi, Gholamreza Bahari, Tahereh Khalili, Courtney Clark, Saeid Ghavami and Mohsen Taheri
    Citation: Translational Medicine Communications 2021 6:26
    Content type: Research Published on:

  41. The novel SARS-CoV-2 has caused the coronavirus disease 2019 (COVID-19) pandemic. Currently, with insufficient worldwide vaccination rates, identifying treatment solutions to reduce the impact of the virus is ...

    Authors: Yendry Ventura-Carmenate, Fatima Mohammed Alkaabi, Yandy Marx Castillo-Aleman, Carlos Agustin Villegas-Valverde, Yasmine Maher Ahmed, Pierdanilo Sanna, Ayesha Abdulla Almarzooqi, Abeer Abdelrazik, Gina Marcela Torres-Zambrano, Maura Wade-Mateo, David Quesada-Saliba, Loubna Abdel Hadi, Antonio Alfonso Bencomo-Hernandez and Rene Antonio Rivero-Jimenez
    Citation: Translational Medicine Communications 2021 6:25
    Content type: Research Published on:

  42. Mesenchymal Stem Cells (MSCs) are multipotent cells with low immuonogenecity, and dynamic tissue repair potential, which explains the overwhelming attention they have attracted in regenerative therapy. One not...

    Authors: Mandana Mohyeddin Bonab, Fatemeh Talebian, Aida Borzabadi, Vahideh Nasr, Azam Abedi Kooshlshahi, Fahime Anisie, Ronaz Haghshenas, Bita Shalbafan, Ehsan Janzamin and Saeed Shahbeigi
    Citation: Translational Medicine Communications 2021 6:24
    Content type: Research Published on:

  44. To evaluate and determine the protective role of statins in COVID-19 patients.

    Authors: Srikanth Umakanthan, Sanjum Senthil, Stanley John, Mahesh K. Madhavan, Jessica Das, Sonal Patil, Ragunath Rameshwaram, Ananya Cintham, Venkatesh Subramaniam, Madhusudan Yogi, Abhishek Bansal, Sumesh Achutham, Chandini Shekar, Vijay Murthy and Robbin Selvaraj
    Citation: Translational Medicine Communications 2021 6:22
    Content type: Research Published on:

  45. Strict adherence to antiretroviral-based microbicide use is important for effective HIV prevention. We previously developed a composite measure of product adherence, protocol compliance, and semen exposure for...

    Authors: Terry A. Jacot, Meredith R. Clark, Oluwatosin E. Adedipe, Susan Godbout, Tina Cunningham, Susan Ju, Jill L. Schwartz, Sinead Delany-Moretlwe, Andrea R. Thurman and Gustavo F. Doncel
    Citation: Translational Medicine Communications 2021 6:21
    Content type: Research Published on:

  46. The majority of COVID-19 research has been devoted to characterizing the epidemiology and early clinical aspects of the virus. In Lagos, Nigeria, we looked at the temporal progression of COVID-19 patients. We ...

    Authors: JP. C. Mbagwu, J. O. Olajugba, Paula-Peace James-Okoro and Obidike Blessing
    Citation: Translational Medicine Communications 2021 6:20
    Content type: Research Published on:

  47. Authors: Santosh Kesari, Gregory C. Kasper, Lev Verkh, Terese C. Hammond, Marla L. Matal, Jay W. Hammerling, Nikolai Tankovich, Adrianus P. Lim, Kevin H. Zhao, Tiffany Juarez, Roberta E. Redfern, Jaya M. Gill, Natsuko Nomura, Audrey Hiemer, Annie Heng and Jessica Shoemaker
    Citation: Translational Medicine Communications 2021 6:19
    Content type: Correction Published on:

    The original article was published in Translational Medicine Communications 2021 6:16

  49. Accurate prediction and early recognition of type II diabetes (T2DM) will lead to timely and meaningful interventions, while preventing T2DM associated complications. In this context, machine learning (ML) is ...

    Authors: Eric Adua, Emmanuel Awuni Kolog, Ebenezer Afrifa-Yamoah, Bright Amankwah, Christian Obirikorang, Enoch Odame Anto, Emmanuel Acheampong, Wei Wang and Antonia Yarney Tetteh
    Citation: Translational Medicine Communications 2021 6:17
    Content type: Research Published on:

  50. Authors: Santosh Kesari, Gregory C. Kasper, Lev Verkh, Terese C. Hammond, Marla L. Matal, Jay W. Hammerling, Nikolai Tankovich, Adrianus P. Lim, Kevin H. Zhao, Tiffany Juarez, Roberta E. Redfern, Jaya M. Gill, Natsuko Nomura, Audrey Hiemer, Annie Heng and Jessica Shoemaker
    Citation: Translational Medicine Communications 2021 6:16
    Content type: Commentary Published on:

    The Correction to this article has been published in Translational Medicine Communications 2021 6:19

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Translational Medicine Communications

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